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Article

Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.

Bone - 1 Dec 2017

Simon Dominic, Derer Anja, Andes Fabian T, Lezuo Patrick, Bozec Aline, Schett Georg, Herrmann Martin, Harre Ulrike

Abstract excerpt

Bone tissue undergoes permanent and lifelong remodeling with a concerted action of bone-building osteoblasts and bone-resorbing osteoclasts. A precise cooperation between those two cell types is critical in the complex process of bone renewal. Galectin-3 is a member of the β-galactoside-binding lectin family playing multiple roles in cell growth, differentiation and aggregation. As it has been described to be...

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Identifiers

PMID: 28822790
DOI: 10.1016/j.bone.2017.08.013

Genes

TRAF6

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