Article
Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration.
Molecular cell - 5 May 2006
Amiott Elizabeth A, Jaehning Judith A
Abstract excerpt
The information encoded in both the nuclear and mitochondrial genomes must be coordinately regulated to respond to changes in cellular growth and energy states. Despite identification of the mitochondrial RNA polymerase (mtRNAP) from several organisms, little is known about mitochondrial transcriptional regulation. Studying the shift from fermentation to respiration in Saccharomyces cerevisiae, we have...
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