Article

Cellular metabolic state controls mitochondrial RNA kinetics

2025-05-15

Abstract excerpt

Human mitochondrial genome encodes essential genes for the oxidative phosphorylation (OXPHOS) complexes. These genes must be transcribed and translated in coordination with nuclear-encoded OXPHOS components to ensure correct stoichiometry during OXPHOS complex assembly in the mitochondria. While much is known about nuclear gene regulation during metabolic stresses like glucose deprivation, little is known about th...

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Literature Corpus work: 262b902b-898d-5537-a34f-b5c02c1d9395
DOI: 10.1101/2025.05.13.653903

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