Article
The impact of imprecisely measured covariates on estimating gene-environment interactions.
BMC medical research methodology - 4 May 2006
Greenwood Darren C, Gilthorpe Mark S, Cade Janet E
Abstract excerpt
BACKGROUND: The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention. In particular, the effects of confounder measurement error on gene-environment interactions are unknown. METHODS: We investigate these effects using simulated data and...
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