Accounting for error due to misclassification of exposures in case-control studies of gene-environment interaction.

Abstract excerpt

We consider analysis of data from an unmatched case-control study design with a binary genetic factor and a binary environmental exposure when both genetic and environmental exposures could be potentially misclassified. We devise an estimation strategy that corrects for misclassification errors and also exploits the gene-environment independence assumption. The proposed corrected point estimates and confidence...

Topics

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• Bias
• Case-Control Studies
• Classification
• Data Interpretation, Statistical
• Environmental Exposure