Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A systematic review of genetic polymorphisms and breast cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 1999

Dunning A M, Healey C S, Pharoah P D, Teare M D, Ponder B A, Easton D F

Abstract excerpt

Studies investigating the relationship between common genetic variants and cancer risk are being reported with rapidly increasing frequency. We have identified 46 published case-control studies that have examined the effect of common alleles of 18 different genes on breast cancer risk. Of these, 12 report statistically significant associations, none of which were reported by more than one study. However, many of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 10548311

Genes

BRCA1
COMT
GSTM1
GSTP1
GSTT1
NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A systematic review of genetic polymorphisms and breast cancer risk.PMID 10548311Read ↗

Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls.Semantic proximity Read ↗

Genetic polymorphisms, the metabolism of estrogens and breast cancer: a review.Semantic proximity Read ↗

Positive association of polymorphisms in estrogen biosynthesis gene, CYP19A1, and metabolism, GST, in breast cancer susceptibility.Semantic proximity Read ↗

Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium.Semantic proximity Read ↗

Evaluation of breast cancer risk in a multigenic model including low penetrance genes involved in xenobiotic and estrogen metabolisms.Semantic proximity Read ↗

CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case-control study.Semantic proximity Read ↗

Analysis of CYP17, CYP19 and CYP1A1 Gene Polymorphisms in Iranian Women with Breast Cancer.Semantic proximity Read ↗

CYP17 and breast cancer: no overall effect, but what about interactions?Semantic proximity Read ↗

Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.Semantic proximity Read ↗

A multigenic study on breast cancer risk associated with genetic polymorphisms of ER Alpha, COMT and CYP19 gene in BRCA1/BRCA2 negative Shanghai women with early onset breast cancer or affected relatives.Semantic proximity Read ↗

Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility.Semantic proximity Read ↗

CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.