Article
Clinical behavior of multiple sclerosis is modulated by the MHC class I-chain-related gene A.
Tissue antigens - 1 May 2006
Fdez-Morera J L, Tunon A, Rodriguez-Rodero S, Rodrigo L, Martinez-Borra J, Gonzalez S, Lopez-Vazquez A, Lahoz C H, Lopez-Larrea C
Abstract excerpt
It is well known that certain HLA class II alleles confer an increased risk for developing multiple sclerosis (MS). Recent studies have suggested HLA class I as a region that may also contribute to the development of MS. In this study, we investigated the association between HLA-DR, HLA-B alleles, and major histocompatibility complex (MHC) class I-chain-related gene A (MICA) transmembrane (MICA-TM) polymorphisms...
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