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Article

B-cell activating factor gene variants in multiple sclerosis: Possible associations with disease susceptibility among females.

Clinical immunology (Orlando, Fla.) - 1 Dec 2023

Skarlis Charalampos, Papadopoulos Vassilis, Raftopoulou Sylvia, Mavragani Clio P, Evangelopoulos Maria-Eleftheria

Abstract excerpt

Although B cells and B cell activating factor (BAFF) have been previously implicated in MS pathogenesis, data regarding the genetic influence of BAFF polymorphisms on MS susceptibility are limited. Here we aim to explore whether BAFF polymorphisms could contribute to MS susceptibility. 156 RRMS patients fulfilling the revised McDonald criteria for MS diagnosis and 220 HCs were enrolled. Clinical, laboratory, and...

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PMID: 37995946
DOI: 10.1016/j.clim.2023.109847

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