Article
The regulation of exosome secretion: a novel function of the p53 protein.
Cancer research - 1 May 2006
Yu Xin, Harris Sandra L, Levine Arnold J
Abstract excerpt
The p53 protein responds to stress signals by regulating the transcription of a variety of genes. Some of these genes encode secreted proteins that may be involved in the communication between adjacent cells. In this study, a proteomics approach was employed to identify proteins secreted by cells in a p53-dependent manner after DNA damage. In addition to the known transcriptional targets of p53, a set of proteins...
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