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Hsp60 Is Actively Secreted by Human Tumor Cells

15 Feb 2010

Abstract excerpt

BACKGROUND: Hsp60, a Group I mitochondrial chaperonin, is classically considered an intracellular chaperone with residence in the mitochondria; nonetheless, in the last few years it has been found extracellularly as well as in the cell membrane. Important questions remain pertaining to extracellular Hsp60 such as how generalized is its occurrence outside cells, what are its extracellular functions and the...

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PMID: 20169074
DOI: 10.1371/journal.pone.0009247

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