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Article

PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts.

Arthritis research & therapy - 5 Nov 2015

Rodriguez-Rodriguez Luis, Ivorra-Cortes Jose, Carmona F David, Martín Javier, Balsa Alejandro, van Steenbergen Hanna W, van der Helm-van Mil Annette H M, González-Álvaro Isidoro, Fernandez-Gutiérrez Benjamín

Abstract excerpt

INTRODUCTION: Prostaglandin E receptor 4 (PTGER4) is implicated in immune regulation and bone metabolism. The aim of this study was to analyze its role in radiological joint damage in rheumatoid arthritis (RA). METHODS: Six independent cohorts of patients with RA of European or North American descent were included, comprising 1789 patients with 5083 sets of X-rays. The Hospital Clínico San Carlos Rheumatoid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26538147
DOI: 10.1186/s13075-015-0830-z
PMCID: PMC4634155

Genes

PTGER4

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