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Article

Interleukin-1?, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: Relationship to occurrence and severity of rheumatoid arthritis

1 Jun 1999

Abstract excerpt

OBJECTIVE: To test if interleukin-1beta (IL-1beta), IL-1 receptor antagonist (IL-1Ra), IL-4, or IL-10 gene polymorphisms could be used as markers of susceptibility or severity in rheumatoid arthritis (RA). METHODS: The study included 108 patients with early RA followed up for 2 years and 128 healthy controls. From genomic DNA, 6 polymorphisms in genes for IL-1beta, IL-1Ra, IL-10, and IL-4 were typed. Allelic...

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Identifiers

PMID: 10366101
DOI: 10.1002/1529-0131(199906)42:6<1093::aid-anr5>3.0.co;2-p

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Source receipt: pubmed, retrieved 7 Sept 2026.

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