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Article

Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: an observational cohort study.

International immunopharmacology - 1 Feb 2015

Davis Marshall L R, LeVan Tricia D, Yu Fang, Sayles Harlan, Sokolove Jeremy, Robinson William, Michaud Kaleb, Thiele Geoffrey M, Mikuls Ted R

Abstract excerpt

OBJECTIVE: To examine the associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms (SNPs) with disease progression in rheumatoid arthritis (RA). METHODS: A total of 1188 RA patients were genotyped for TLR4 SNPs (rs1927911, rs11536878, and rs4986790). Measures of disease activity were examined, including Disease Activity Score-28 (DAS28), Multidimensional Health Assessment Questionnaire (MD-HAQ),...

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Source

Identifiers

PMID: 25573402
DOI: 10.1016/j.intimp.2014.12.030

Genes

TLR4

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