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Article

Ovarian stem cells: absence of evidence is not evidence of absence

1 Jan 2013

Abstract excerpt

BACKGROUND: Lei and Spradling in a recent study published in PNAS failed to detect 'germline cysts' by elegant studies using lineage tracing approach and thus concluded that adult mouse ovaries lack stem cells. They proposed that primordial follicle pool generated during fetal life is sufficient to sustain oogenesis and that there is no renewal of oocytes during adult life. Contrary to their results, we have...

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PMID: 24044496
DOI: 10.1186/1757-2215-6-65

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