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NANOS3 function in human germ cell development

19 Mar 2011

Abstract excerpt

Human infertility is common and frequently linked to poor germ cell development. Yet, human germ cell development is poorly understood, at least in part due to the inaccessibility of germ cells to study especially during fetal development. Here, we explored the function of a highly conserved family of genes, the NANOS genes, in the differentiation of human germ cells from human embryonic stem cells. We observed...

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PMID: 21421998
DOI: 10.1093/hmg/ddr114

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