Article
Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.
Molecular biology of the cell - 1 Jul 2006
Babbey Clifford M, Ahktar Nahid, Wang Exing, Chen Carlos Chih-Hsiung, Grant Barth D, Dunn Kenneth W
Abstract excerpt
Rab10, a protein originally isolated from Madin-Darby Canine Kidney (MDCK) epithelial cells, belongs to a family of Rab proteins that includes Rab8 and Rab13. Although both Rab8 and Rab13 have been found to mediate polarized membrane transport, the function of Rab10 in mammalian cells has not yet been established. We have used quantitative confocal microscopy of polarized MDCK cells expressing GFP chimeras of...
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