Article
Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin.
Molecular biology of the cell - 1 Apr 2005
Lock John G, Stow Jennifer L
Abstract excerpt
E-cadherin plays an essential role in cell polarity and cell-cell adhesion; however, the pathway for delivery of E-cadherin to the basolateral membrane of epithelial cells has not been fully characterized. We first traced the post-Golgi, exocytic transport of GFP-tagged E-cadherin (Ecad-GFP) in unpolarized cells. In live cells, Ecad-GFP was found to exit the Golgi complex in pleiomorphic tubulovesicular carriers,...
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