Article
Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects.
Experimental cell research - 1 Oct 2004
Saras Jan, Wollberg Patrick, Aspenström Pontus
Abstract excerpt
The Rho family of small GTPases controls many biological processes, including cytoskeletal regulation, membrane trafficking, cell adhesion, cell polarization, transcriptional activity, apoptosis, and cell proliferation. Wrch1, which belongs to the Cdc42 subfamily, is one of the least characterized family member. Despite its homology to other Cdc42-like proteins, we found that Wrch1 has unique characteristics....
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