Article

A toxic palmitoylation on Cdc42 drives a severe autoinflammatory syndrome

2019-10-17

Abstract excerpt

<h4>Background</h4> Autoinflammatory diseases (AID) result from dysregulation of the first lines of innate immune responses. Recently, development of high throughput genome sequencing technology led to the rapid emergence of important knowledge in the genetic field. About 20 genes have been identified so far in monogenic forms of distinct AID. However, 70-90 % of patients with AID remain without genetic diagnosis...

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Literature Corpus work: 338126a3-ca94-50e1-b243-1d51191e94c6
DOI: 10.1101/808782

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