Article
In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Apr 2006
Bock Nicholas A, Kovacevic Natasa, Lipina Tatiana V, Roder John C, Ackerman Susan L, Henkelman R Mark
Abstract excerpt
Magnetic resonance imaging and computer image analysis in human clinical studies effectively identify abnormal neuroanatomy in disease populations. As more mouse models of neurological disorders are discovered, such an approach may prove useful for translational studies. Here, we demonstrate the effectiveness of a similar strategy for mouse neuroscience studies by phenotyping mice with the cerebellar deficient...
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