Article
Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography.
Physiological genomics - 12 Jan 2006
Nieman Brian J, Flenniken Ann M, Adamson S Lee, Henkelman R Mark, Sled John G
Abstract excerpt
Since genetically modified mice have become more common in biomedical research as models of human disease, a need has also grown for efficient and quantitative methods to assess mouse phenotype. One powerful means of phenotyping is characterization of anatomy in mutant vs. normal populations. Anatomical phenotyping requires visualization of structures in situ, quantification of complex shape differences between...
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