Article
MRI phenotyping of genetically altered mice.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Lerch Jason P, Sled John G, Henkelman R Mark
Abstract excerpt
The laboratory mouse, with its genetic similarity to humans and rich set of tools for manipulating its genome, has emerged as one of the key models for experimental investigation of the genotype/phenotype relationships in mammals. Recent innovations have made MRI an increasingly popular tool for examining the phenotype of genetically altered mice. Advances in field strengths, mouse handling, image analysis and...
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