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Article

Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion.

Molecular psychiatry - 1 Jan 2014

Ellegood J, Markx S, Lerch J P, Steadman P E, Genç C, Provenzano F, Kushner S A, Henkelman R M, Karayiorgou M, Gogos J A

Abstract excerpt

Recurrent deletions at the 22q11.2 locus have been established as a strong genetic risk factor for the development of schizophrenia and cognitive dysfunction. Individuals with 22q11.2 deletions have a range of well-defined volumetric abnormalities in a number of critical brain structures. A mouse model of the 22q11.2 deletion (Df(16)A(+/-)) has previously been utilized to characterize disease-associated...

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Identifiers

PMID: 23999526
DOI: 10.1038/mp.2013.112
PMCID: PMC3872255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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