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Article

The role of LPA1 in formation of synapses among cultured hippocampal neurons.

Journal of neurochemistry - 1 Jun 2006

Pilpel Yair, Segal Menahem

Abstract excerpt

We studied the lysophosphatidic acid receptor-1 (LPA1) gene, which we found to be expressed endogenously in cultured hippocampal neurons, and in vivo in young (1-week-old) rat brain slices. Overexpressed green fluorescent protein (GFP)-tagged, membrane-associated LPA1 accumulated in a punctate manner over the entire dendritic tree and caused an increase in dendritic spine density. About half of the dendritic...

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Identifiers

PMID: 16638019
DOI: 10.1111/j.1471-4159.2006.03825.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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