Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat.

The Journal of physiology - 1 Apr 2003

Losi Gabriele, Prybylowski Kate, Fu Zhanyan, Luo Jianhong, Wenthold Robert J, Vicini Stefano

Abstract excerpt

We transfected a green fluorescent protein-tagged PSD-95 (PSD-95gfp) into cultured rat cerebellar granule cells (CGCs) to investigate the role of PSD-95 in excitatory synapse maturation. Cells were grown in low potassium to favour functional synapse formation in vitro. Transfected cells displayed clear clusters of PSD-95gfp, often at the extremities of the short dendritic trees. We recorded NMDA and AMPA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebellum
Share to Disks Large Homolog 4 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophysiology

Share to Excitatory Amino Acid Antagonists

Share to Membrane Potentials

Share to Piperidines

Share to Receptors, N-Methyl-D-Aspartate

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 12576494
DOI: 10.1113/jphysiol.2002.034918
PMCID: PMC2342804

Genes

PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat.PMID 12576494Read ↗

NMDA receptor subtypes at autaptic synapses of cerebellar granule neurons.Semantic proximity Read ↗

NMDA receptor NR2B subunit over-expression increases cerebellar granule cell migratory activity.Semantic proximity Read ↗

Modulation of the channel activity of the epsilon2/zeta1-subtype N-methyl D-aspartate receptor by PSD-95.Semantic proximity Read ↗

Distinct kainate receptor phenotypes in immature and mature mouse cerebellar granule cells.Semantic proximity Read ↗

Impact of NRSN2 Deficiency on Memory: Disruption of Excitatory Synaptic Plasticity Linked to Reduced Expression of NMDA Receptor Subunits and impaired LTP in the hippocampusSemantic proximity Read ↗

Survival and synaptogenesis of hippocampal neurons without NMDA receptor function in culture.Semantic proximity Read ↗

Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation.Semantic proximity Read ↗

Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity.Semantic proximity Read ↗

Further characterization of the molecular interaction between PSD-95 and NMDA receptors: the effect of the NR1 splice variant and evidence for modulation of channel gating.Semantic proximity Read ↗

GluN2A-mediated currents and calcium signal in human iPSC-derived neuronsSemantic proximity Read ↗

Characterization in cultured cerebellar granule cells and in the developing rat brain of mRNA variants for the NMDA receptor 2C subunit.Semantic proximity Read ↗

Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.