Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Combined breast conservation therapy versus mastectomy for BRCA mutation carriers - A systematic review and meta-analysis.

Breast (Edinburgh, Scotland) - 1 Apr 2021

Davey M G, Davey C M, Ryan É J, Lowery A J, Kerin M J

Abstract excerpt

BACKGROUND: The non-inferiority of combined breast conservation surgery (BCS) and radiotherapy (breast conservation therapy or BCT) compared to mastectomy in sporadic breast cancer cases is well recognised. Uncertainty remains regarding optimal surgical practice in BRCA mutation carriers. AIMS: To evaluate the oncological safety of combined BCT versus mastectomy in BRCA mutation carriers following breast cancer...

Topics

Breast Neoplasms
Female
Genes, BRCA2
Humans
Mastectomy
Mastectomy, Segmental
Mutation
Neoplasm Recurrence, Local
Radiotherapy, Adjuvant

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 33582622
DOI: 10.1016/j.breast.2021.02.001
PMCID: PMC7887648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined breast conservation therapy versus mastectomy for BRCA mutation carriers - A systematic review and meta-analysis.PMID 33582622Read ↗

Breast Conserving Surgery for BRCA Mutation Carriers-A Systematic Review.Semantic proximity Read ↗

Does breast-conserving surgery with radiotherapy in BRCA-mutation carriers significantly increase ipsilateral breast tumor recurrence? A systematic review and meta-analysis.Semantic proximity Read ↗

Surgical management of breast cancer in BRCA-mutation carriers: a systematic review and meta-analysis.Semantic proximity Read ↗

Breast-conserving therapy for breast cancer with BRCA mutations: a meta-analysis.Semantic proximity Read ↗

Does bilateral mastectomy affect clinical outcomes in BRCA1/2 mutation carriers with primary breast cancer? A systematic review and meta-analysis.Semantic proximity Read ↗

Breast cancer treatment in mutation carriers: surgical treatment.Semantic proximity Read ↗

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study.Semantic proximity Read ↗

Impact of breast surgical procedure on survival in BRCA mutated patients with invasive breast cancer: Mastectomy versus conservative treatment.Semantic proximity Read ↗

Bilateral risk-reduction mastectomy in BRCA1 and BRCA2 mutation carriers: a meta-analysis.Semantic proximity Read ↗

BRCA1/2 Mutation-associated Breast Cancer, Wide Local Excision and Radiotherapy or Unilateral Mastectomy: A Systematic Review.Semantic proximity Read ↗

Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy.Semantic proximity Read ↗

Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.