Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conservative management of breast cancer in BRCA1/2 mutation carriers.

Clinical breast cancer - 1 Apr 2004

Alpert Tracy E, Haffty Bruce G

Abstract excerpt

Breast-conserving therapy is widely embraced for the majority of women with early-stage breast cancer, but its appropriateness in patients with germline mutations of BRCA1 and BRCA2 remains controversial. These breast cancer susceptibility genes are associated with a progressive risk of second cancers, although the prognosis of BRCA-associated breast cancer is similar to that in patients with sporadic disease....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neoplasm Recurrence, Local
Share to Anticarcinogenic Agents
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Breast Neoplasms

Share to Neoplasms, Second Primary

Share to Radiotherapy Dosage

Share to Tamoxifen

Source

Identifiers

PMID: 15140283
DOI: 10.3816/cbc.2004.n.008

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conservative management of breast cancer in BRCA1/2 mutation carriers.PMID 15140283Read ↗

Radiotherapy for breast cancer in BRCA1/BRCA2 carriers: clinical issues and management dilemmas.Semantic proximity Read ↗

Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.Semantic proximity Read ↗

Clinical management of women with genomic BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Surgical management of breast cancer in BRCA-mutation carriers: a systematic review and meta-analysis.Semantic proximity Read ↗

Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.Semantic proximity Read ↗

Impact of breast surgical procedure on survival in BRCA mutated patients with invasive breast cancer: Mastectomy versus conservative treatment.Semantic proximity Read ↗

Therapeutic approaches for women predisposed to breast cancer.Semantic proximity Read ↗

Prevention of breast cancer in women who carry BRCA1 or BRCA2 mutations: a critical review of the literature.Semantic proximity Read ↗

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a critical review of the literature.Semantic proximity Read ↗

BRCA Mutation Testing in Determining Breast Cancer TherapySemantic proximity Read ↗

Hereditary breast cancer: clinical features and risk reduction strategies.Semantic proximity Read ↗

Breast cancer treatment in mutation carriers: surgical treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.