TNF-alpha, the great imitator: role of p55 and p75 TNF receptors in hematopoiesis.

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Article

TNF-alpha, the great imitator: role of p55 and p75 TNF receptors in hematopoiesis.

Stem cells (Dayton, Ohio) - 1 Jan 1994

Jacobsen S E, Jacobsen F W, Fahlman C, Rusten L S

Abstract excerpt

The clinical application of tumor necrosis factor-alpha (TNF-alpha) has so far been limited due to the severe adverse effects associated with its systemic use. Recently, two distinct TNF receptors with molecular weights of 55 kDa (TNFR55) and 75 kDa (TNFR75) have been cloned and characterized. Th...

Topics

Animals
Antigens, CD
Cloning, Molecular
Hematopoiesis
Hematopoietic Cell Growth Factors
Hematopoietic Stem Cells
Humans
In Vitro Techniques
Membrane Proteins
Mice
Mutation
Receptors, Cytokine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Tumor Necrosis Factor

Receptors, Tumor Necrosis Factor, Type I

Receptors, Tumor Necrosis Factor, Type II

Signal Transduction

Stem Cell Factor

Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 7535144

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7535144-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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