The anemia of malaria infection: role of inflammatory cytokines.

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Article

The anemia of malaria infection: role of inflammatory cytokines.

Current hematology reports - 1 Mar 2004

McDevitt Michael A, Xie Jianlin, Gordeuk Victor, Bucala Richard

Abstract excerpt

Death from malaria occurs from the complications of the infection: cerebral manifestations leading to coma and a severe and refractory anemia leading to hypoxia and cardiac decompensation. Several mechanisms have been identified to play a role in the pathogenesis of malarial anemia, such as erythrocyte lysis and phagocytosis, and sequestration of parasitized red blood cells, but recent data indicate that these...

Topics

Adult
Anemia
Animals
Aotus trivirgatus
Bone Marrow
Child
Child, Preschool
Cytokines
Erythropoiesis
Erythropoietin
Genetic Predisposition to Disease
Heart Failure
Humans
Hypoxia
Infant
Inflammation Mediators
Malaria
Malaria Vaccines

Source

Open in PubMed

Identifiers

PMID: 14965485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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