Article
Polyomavirus middle T-antigen NPTY mutants.
Journal of virology - 1 Oct 1992
Druker B J, Sibert L, Roberts T M
Abstract excerpt
A polyomavirus middle T-antigen (MTAg) mutant containing a substitution of Leu for Pro at amino acid 248 has previously been described as completely transformation defective (B. J. Druker, L. Ling, B. Cohen, T. M. Roberts, and B. S. Schaffhausen, J. Virol. 64:4454-4461, 1990). This mutant had no...
Topics
- 1-Phosphatidylinositol 4-Kinase
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Antigens, Polyomavirus Transforming
- Base Sequence
- Cell Line
- Methionine
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutagenesis, Insertional
- Mutation
- Phosphotransferases
- Precipitin Tests
- Protein-Tyrosine Kinases
- Transformation, Genetic