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Article

Methylation and repeats in silent and nonsense mutations of p53.

Mutation research - 25 Jul 2006

Kouidou Sofia, Malousi Andigoni, Maglaveras Nicos

Abstract excerpt

All exonic CG sequences in p53 are methylated; this epigenetic modification is correlated with frequent G:C-->A:T transitions in p53. Recent reports reveal the presence in p53 of non-CG methylation in CC and CCC sequences, complementary to sites of selective guanosine adduct formation (GG and GGG), and the association of genetic instability with methylation at repetitive sequences. We presently investigated the...

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PMID: 16620878
DOI: 10.1016/j.mrfmmm.2006.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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