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Article

Effects of normal and mutant ras genes on inositol lipid metabolism in Dictyostelium.

Cellular signalling - 1 Jan 1991

Wood C A, Europe-Finner G N, Newell P C

Abstract excerpt

Dictyostelium cells transformed with multiple copies of a mutant Dictyostelium ras gene (ras-Thr12 that gave a Gly to Thr substitution at position 12 of the ras protein, showed 2 to 3 times greater incorporation of 32P into PtdInsP and PtdInsP2 (without changing the specific radioactivity) compared to the untransformed strain or a strain transformed with multiple copies of the normal ras-Gly12 gene. The ratio of...

Topics

Aluminum
Aluminum Compounds
Animals
Cyclic AMP
Dictyostelium
Fluorides
Fluorine
Genes, ras
Inositol 1,4,5-Trisphosphate
Kinetics
Mutation
Phosphatidylinositols

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Source

Identifiers

PMID: 1662065
DOI: 10.1016/0898-6568(91)90077-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1662065-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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