Article
Search on chromosome 17 centromere reveals TNFRSF13B as a susceptibility gene for intracranial aneurysm: a preliminary study.
Circulation - 25 Apr 2006
Inoue Kayoko, Mineharu Youhei, Inoue Sumiko, Yamada Shigeki, Matsuda Fumihiko, Nozaki Kazuhiko, Takenaka Katsunobu, Hashimoto Nobuo, Koizumi Akio
Abstract excerpt
BACKGROUND: Our previous studies have shown a significant linkage of intracranial aneurysms (IAs) to chromosome 17. METHODS AND RESULTS: Nine genes (TNFRSF13B, M-RIP, COPS3, RAI1, SREBF1, GRAP, MAPK7, MFAP4, and AKAP10) were selected from 108 genes that are located between D17S1857 and D17S1871 by excluding 99 genes that were pseudogenes, hypothetical genes, or well-characterized genes but not likely associated...
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