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Article

Genetic study of intracranial aneurysms.

Stroke - 1 Mar 2015

Yan Junxia, Hitomi Toshiaki, Takenaka Katsunobu, Kato Masayasu, Kobayashi Hatasu, Okuda Hiroko, Harada Kouji H, Koizumi Akio

Abstract excerpt

BACKGROUND AND PURPOSE: Rupture of intracranial aneurysms (IAs) causes subarachnoid hemorrhage, leading to immediate death or severe disability. Identification of the genetic factors involved is critical for disease prevention and treatment. We aimed to identify the susceptibility genes for IAs. METHODS: Exome sequencing was performed in 12 families with histories of multiple cases of IA (number of cases per...

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Source

Identifiers

PMID: 25649796
DOI: 10.1161/STROKEAHA.114.007286

Genes

ADAMTS15
GPR63
PAFAH2
THBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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