Article
Study of association between hypertensive disorders of pregnancy and the human coagulation factor XI gene.
Hypertension in pregnancy - 1 Jan 2006
Sato Ichiro, Nakayama Tomohiro, Maruyama Aya, Furuya Kiyohide, Sato Naoyuki, Mizutani Yoshihiro, Yamamoto Tatsuo
Abstract excerpt
OBJECTIVE: Hypertensive disorders of pregnancy (HDP) are among the most common and serious complications of pregnancy. Persuasive evidence implicaties genetic factors in the genesis of HDP. The aim of the present study was to assess the association between single-nucleotide polymorphisms (SNPs) in the human coagulation factor XI (F11) gene and HDP, by conducting a haplotype-based case-control study. METHODS: We...
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