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Article

Functional investigation of a venous thromboembolism GWAS signal in a promoter region of coagulation factor XI gene.

Molecular biology reports - 1 Jan 2014

Kong Minyoung, Kim Younyoung, Lee Chaeyoung

Abstract excerpt

Coagulation factor XI (FXI) is essential for normal function of the intrinsic pathway of blood coagulation. A nucleotide variant (rs3756008) in the promoter region of the FXI gene was recently reported for association with venous thromboembolism. This study aimed to examine promoter activity of the rs3756008 or other variants linked with it. Luciferase assay was analyzed with minigenes including haplotypes (AA...

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PMID: 24420855
DOI: 10.1007/s11033-014-3049-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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