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Article

Factor 11 single-nucleotide variants in women with heavy menstrual bleeding.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Oct 2017

Wiewel-Verschueren Sophie, Mulder André B, Meijer Karina, Mulder René

Abstract excerpt

In a previous study it was shown that lower factor XI (FXI) levels in women with heavy menstrual bleeding (HMB). Our aim was to determine the single-nucleotide variants (SNVs) in the F11 gene in women with HMB. In addition, an extensive literature search was performed to determine the clinical significance of each SNV. Patients referred for HMB (PBAC-score >100) were included. With direct sequencing analysis of...

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PMID: 28609141
DOI: 10.1080/01443615.2017.1312303

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IMPACT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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