Article
Association between ACVR2A gene polymorphisms and risk of hypertensive disorders of pregnancy in the northern Chinese population.
Placenta - 15 Jan 2020
Yanan Feng, Rui Lu, Xiaoying Li, Shuang Zhang, Feng Zhang, Yingnan Wu, Tianshuang Jia, Xuan Yang, Xiaolei Yuan, Litao Sun
Abstract excerpt
INTRODUCTION: To investigate the possible roles of selected single-nucleotide gene polymorphisms (SNPs) of the activin A receptor type 2A (ACVR2A) gene in the pathogenesis of hypertensive disorders of pregnancy (HDP). METHODS: In this study, the six SNPs of the ACVR2A gene were analyzed by multiplex polymerase chain reaction (PCR) combined with next-generation sequencing methods in 186 HDP patients and 380...
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