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PI3K/AKT Signaling Tips the Balance of Cytoskeletal Forces for Cancer Progression

24 Mar 2022

Abstract excerpt

The PI3K/AKT signaling pathway plays essential roles in multiple cellular processes, which include cell growth, survival, metabolism, and motility. In response to internal and external stimuli, the PI3K/AKT signaling pathway co-opts other signaling pathways, cellular components, and cytoskeletal proteins to reshape individual cells. The cytoskeletal network comprises three main components, which are namely the...

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PMID: 35406424
DOI: 10.3390/cancers14071652

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