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Article

Interaction between GSTM1-null and CYP2D6-deficient alleles in the pathogenesis of Parkinson's disease.

European journal of neurology - 1 Apr 2004

Santt O, Baranova H, Albuisson E, Bignon Y-J, Lucotte G

Abstract excerpt

The present study was conducted to examine the interaction between cytochrome p450 2D6: CYP2D6 (phase I) poor metabolizer (PM) and glutathione S-transferase M1: GSTM1 (phase II) null genotypes, among 103 unrelated French Parkinson's disease (PD) patients. Both genes are involved in the biotransformation process, and the main objective of that work is to assess synergic effect between CYP2D6 PM and GSTM1 null...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15061826
DOI: 10.1046/j.1468-1331.2003.00756.x

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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