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Article

Genetic polymorphism of CYP2D6 influences susceptibility to papillary thyroid cancer.

Clinical endocrinology - 1 Aug 2007

Lemos Manuel C, Carrilho Francisco, Rodrigues Fernando, Coutinho Eduarda, Gomes Leonor, Carvalheiro Manuela, Regateiro Fernando J

Abstract excerpt

OBJECTIVE: Xenobiotic-metabolizing enzymes are widely polymorphic and confer interindividual variation in the ability to detoxify carcinogens or to activate pro-carcinogens. A common polymorphism of cytochrome P450 2D6 (CYP2D6) results in lack of enzyme activity and has been associated with an altered susceptibility to several cancers. The aim of this study was to investigate the association between the CYP2D6...

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Identifiers

PMID: 17547692
DOI: 10.1111/j.1365-2265.2007.02858.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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