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Article

TNF-857 polymorphism in Israeli Jewish patients with inflammatory bowel disease.

International journal of immunogenetics - 1 Apr 2006

Fidder Herma H, Heijmans Roel, Chowers Yehuda, Bar-Meir Simon, Avidan Benjamin, Pena A Salvador, Crusius J Bart A

Abstract excerpt

Tumour necrosis factor (TNF)-alpha is an important pro-inflammatory cytokine that has been implicated in the pathogenesis of inflammatory bowel disease (IBD). The promoter TNF-857 C-->T single nucleotide polymorphism (SNP) is functional through the binding to the transcription factor octamer transcription factor-1 (OCT-1). In order to investigate the frequency of this SNP in Israeli Jewish IBD patients, we...

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Identifiers

PMID: 16611251
DOI: 10.1111/j.1744-313X.2006.00572.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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