Article
TNF-alpha gene polymorphisms in Iranian Azari Turkish patients with inflammatory bowel diseases.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000
Bonyadi Mortaza, Abdolmohammadi Reza, Jahanafrooz Zohreh, Somy Mohammad-Hosein, Khoshbaten Manoochehr
Abstract excerpt
CONTEXT: Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the bowel (IBD) whose causes are not fully known. Emerging data indicate that alterations in cytokine synthesis may play a role in IBD pathogenesis. AIMS: We aimed to determine the association between tumor necrosis factor-alfa (TNFα) promoter polymorphisms (at positions - 308 and - 1031) and susceptibility to IBD among...
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