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Article

Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort.

Inflammatory bowel diseases - 1 Mar 2006

Tremelling Mark, Waller Sarah, Bredin Francesca, Greenfield Simon, Parkes Miles

Abstract excerpt

BACKGROUND: Genetic variants in DLG5, which encodes a scaffolding protein on chromosome 10q23, and tumor necrosis factor (TNF)-alpha, encoding a proinflammatory cytokine on chromosome 6p, have recently been reported to be associated with inflammatory bowel disease (IBD). We studied these variants to seek evidence of association with IBD in a large independent dataset. METHODS: We genotyped 1104 unrelated white...

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Source

Identifiers

PMID: 16534418
DOI: 10.1097/01.MIB.0000217766.90766.37

Genes

TNF
DLG5
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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