Article
Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma.
Rejuvenation research - 1 Jan 2006
Corder Elizabeth H, Hefler Lukas A
Abstract excerpt
We investigated inherited polymorphic variation in genes spanning estrogen metabolism (10 SNPs [single nucleotide polymorphism]) to distinguish multilocus genotypes associated with breast cancer (n = 393), benign breast lesions (n = 154), and low risk (n = 1936). Three latent classification GoM extreme type groups represented the data: (a) fibroadenoma, and infrequent SRD5A2 and VDR alleles; (b) postmenopausal...
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