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Article

Evaluation of breast cancer risk in a multigenic model including low penetrance genes involved in xenobiotic and estrogen metabolisms.

Nutrition and cancer - 1 Jan 2010

Delort Laetitia, Satih Samir, Kwiatkowski Fabrice, Bignon Yves-Jean, Bernard-Gallon Dominique J

Abstract excerpt

Breast cancer has become the most frequent cancer among women in Westernized countries. The majority of breast cancers are due to low penetrance genes, which can act with environmental factors, particularly nutrition. Polymorphisms in gene coding for xenobiotic and estrogen metabolic pathways could increase individual cancer susceptibility and lead to the indication of individuals at higher cancer risk. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20099199
DOI: 10.1080/01635580903305300

Genes

COMT
GSTP1
NAT2

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