Article
Spontaneous mutagenesis in Escherichia coli harbouring plasmid pKM101: DNA sequence analysis of forward lacI- mutations.
Mutagenesis - 1 Mar 1993
Gordon A J, Bernelot-Moens C, Glickman B W
Abstract excerpt
To investigate the influence of plasmid pKM101 on spontaneous mutagenesis, 198 lacI- mutations generated in Escherichia coli harbouring pKM101 were characterized at the DNA sequence level. pKM101 by itself did not enhance the lacI- forward mutation frequency. In general, the resultant distributio...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Composition
- Base Sequence
- DNA Polymerase I
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Frameshift Mutation
- Genes, Bacterial
- Lac Repressors
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Nucleic Acid Conformation
- Phenotype
- Plasmids
- Repressor Proteins