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Article

Determinants of the APTT- and ETP-based APC sensitivity tests.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2005

de Visser M C H, van Hylckama Vlieg A, Tans G, Rosing J, Dahm A E A, Sandset P M, Rosendaal F R, Bertina R M

Abstract excerpt

BACKGROUND: A reduced sensitivity for activated protein C (APC) is associated with an increased risk of venous thrombosis even in the absence of the factor (F)V Leiden mutation. This risk has been demonstrated with two APC sensitivity tests, which quantify the effects of APC on the activated partial thromboplastin time (APTT) and the endogenous thrombin potential (ETP), respectively. OBJECTIVES: We examined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15978106
DOI: 10.1111/j.1538-7836.2005.01430.x

Genes

APC
TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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