Article
Genetic analysis of CAV1 gene in hypertension and metabolic syndrome.
Thrombosis and haemostasis - 1 Apr 2006
Grilo Antonio, Fernandez Maria Luisa, Beltrán Manuel, Ramirez-Lorca Reposo, González María Angeles, Royo Jose Luis, Gutierrez-Tous Reyes, Morón Francisco Jesús, Couto Carmen, Serrano-Rios Manuel, Saez Maria Eugenia, Ruiz Agustin, Real Luis Miguel
Abstract excerpt
Recently, we reported that the polymorphism 1132T>C (GenBank: AF519768.1) of the NOS3 gene was associated with susceptibility to metabolic syndrome (MS) in hypertensive patients. This suggests that other genes such as CAV1, whose product (CAV1) regulates eNOS activity, could also be related to this phenotype. In this work we investigated the following: i) whether CAV1 is a quantitative trait locus of clustering...
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