Article
Association between 894G>T endothelial nitric oxide synthase gene polymorphisms and metabolic syndrome.
Arquivos brasileiros de endocrinologia e metabologia - 1 Nov 2008
Piccoli Jacqueline C Escobar, Gottlieb Maria Gabriela Valle, Castro Luciano, Bodanese Luiz Carlos, Manenti Euler Roberto Fernandes, Bogo Mauricio Reis, Peres Alessandra, Rocha Maria Izabel U M da, Cruz Ivana Beatrice Mânica da
Abstract excerpt
Metabolic syndrome (MS) is a cluster of cardiovascular risk factors such as hypertension, dyslipidemia, obesity and type II diabetes. Here, we performed a case-control study analyzing the association between 894G>T endothelial nitric oxide synthase gene polymorphism (NOS3) and MS in 616 subjects. Genotype frequencies were TT= 9.3%, GG= 37.2 and TG= 53.6% and the allelic frequencies were T=0.36 and G= 0.64. We...
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